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Brain damage is likely to cause a loss of sense of smell in people with coronary heart disease

آسیب به مغز احتمالا باعث از دست دادن حس بویایی در مبتلایان به کرونا می‌شود

Lack of sense of smell and taste One of the main symptoms of coronavirus infection was at the beginning of the epidemic, but researchers are still trying to find the cause. New research suggests that the problem may not be due to direct contact with the virus but to brain damage Inflammation The olfactory tissue is caused by the disease.

Based on a study in the journal JAMA Neurology Published by Body Researchers 23 people Coronation of the dead has been performed. Their findings show that it was not the virus itself but the inflammation caused by the disease that caused the loss of sense of smell and taste. With this account, it can be guessed that the use Anti-inflammatory drugs It can help prevent serious or long-term damage to patients’ senses of smell and taste.

Previous research has suggested that the corona virus can infect nerves that transmit olfactory signals to the brain. But some other research believed that the virus was not present in these nerves at the time of death. In this new study, researchers at Johns Hopkins University examined the olfactory-related tissues of 23 patients who died from coronation and found that 9 people They had completely or partially lost their sense of smell and taste.

Researchers of the olfactory nerves inside the nasal mucosa, blood vessels and number Olfactory axons – measured the same part of the nerves that transmit electrical signals. They also damage the part of the brain that receives olfactory signals and are called Smelling onion Checked to find out if the virus was there.

Inflammation of the corona destroys the sense of smell

The result was that patients with coronary artery disease who lost their sense of smell and taste suffered more damage to the nasal mucosa and circulatory system and had far fewer olfactory axons. However, this communication injury was not strongly related to the patients’ infection. Because some patients with mild infections had serious damage to the olfactory bulb.

In addition, only three person Of the 23 patients studied, they had detectable levels of coronavirus genetic material in their olfactory bulbs, of which only one person He had reported a lack of sense of smell. Therefore, the researchers concluded that damage to the olfactory system was not directly affected by the virus.

“Our findings show that SARS infection in the epithelial tissue of the olfactory system leads to inflammation, and this inflammation leads to Nerves “It damages, as a result of which the number of axons that send signals to the brain decreases and the function of the olfactory bulb is impaired.” This disorder can be so severe that the patient can lose the sense of smell and taste for a long time.

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