Australian researchers have found evidence that bacteria that live in the nose can enter the brain through the nasal cavities and eventually cause Alzheimer’s disease. These studies help scientists study Alzheimer’s disease through viral or bacterial infections.
Chlamydia pneumoniae is a common bacterium worldwide that causes pneumonia and a wide range of other respiratory illnesses. The more worrying news is that this bacterium is sometimes found in the brain and is a major cause of other diseases.
In a New studyResearchers at Griffith University and the University of Queensland have begun studying how the bacterium enters the brain and how it is damaged. The research team had previously studied diseases that a bacterium living in the nasal cavity can cause in the brain.
“In a previous study, we showed how bacteria in the nasal cavity can quickly enter the brain through the cavities and enter the central nervous system in just 24 hours,” said lead author Jenny Akberg.
Bacterial test for Alzheimer’s disease
In experiments performed on mice, the team found that the bacterium Chlamydia pneumoniae could infect the olfactory nerves and then the olfactory bulb, a small nerve structure in the front of the brain that processes olfactory senses, within 72 hours of entering the nose. And access the brain with a short movement.
On the other hand, this bacterium enters the central nervous system and causes changes that are associated with Alzheimer’s disease. For example, scientists have observed “amyloid beta” deposits in the brain, which is a distinctive feature of Alzheimer’s disease.
This new research has provided valuable information for scientists in this field. In recent years, many research groups have sought to link Alzheimer’s to viral and bacterial infections of the nose and mouth. The herpes virus is another suspected candidate. On the other hand, it seems that the bacteria that cause gum disease can also cause Alzheimer’s disease.
“We have been skeptical for a long time about whether bacteria and viruses can cause nerve inflammation,” says Akberg. Although it is possible that a single virus or bacterium may not be the only cause of the disease, research has shown that it plays a key role. “Obviously, other factors, such as genetics and mental activity, also play a role.”
The team believes that finding ways to prevent the bacterium from entering the nose could lead to new and preventative treatments for Alzheimer’s disease.