Researchers want to use combination therapies to counteract muscle wasting with age

پژوهشگران می‌خواهند با درمان‌های ترکیبی، با تحلیل عضلات در اثر افزایش سن مقابله کنند

Man instinctively wants to survive. People want to stay healthy and fit as they get older. However, as we age, our bodies weaken, our muscles shrink, and our physical strength decreases. Some older people are not happy with this situation; A situation referred to in medical science «Sarcopenia” Called. Now university researchers «BaselThey have found a combination therapy that can delay muscle wasting.

As we age, our muscles inevitably lose volume and strength. This age-related issue puts an end to our independent lifestyle and requires us to support the family or the health care system on a daily basis to continue living.

Muscle resorption due to aging

the doctor “Daniel Ham», One of the main authors of this article Says“Age-related muscle loss begins at age 30, but at about age 60, the rate begins to increase. At age 80, we lose about a third of our muscle mass. “Although we can not stop this aging process, for example, with the help of exercise, it can be countered or slowed down.”

Researchers led by «Marcus Rogge“Studies in mice from the University of Basel have shown that calorie restriction, in addition to medication,”RapamycinIt has a positive effect on the aging of skeletal muscles.

the doctor “Nitish Mital“Calorie restriction and rapamycin are both known as anti-aging interventions, but we did not expect these two to have other positive benefits,” said another author of the article.

Combination therapy to reduce muscle wasting

“In our study, we found that mice that had a calorie-restricted program with rapamycin had much better muscle function than mice that used the two anti-aging methods separately,” says Ham. “They were much more active and more physically capable.”

“In addition to affecting physical function, muscles also affect the metabolism of the whole body and the function of many organs,” says Mittal. “They help us to live an active and independent life for a longer period of time and to increase the quality of life and the level of satisfaction in old age.”

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